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Genfit Inc global fitting approach
(Left) Experimental SAXS curves referring to d(pG) at 5 wt% concentration and different temperatures. From the bottom to the top: open squares 296.6 K, open circles 297.7 K, up-triangles 298.6 K, down-triangles 300.8 K, diamonds 302.7 K. The solid lines are the <t>GENFIT</t> <t>global</t> fit curves. The scattering curves are scaled by an appropriate factor for the sake of clarity. (Right) Temperature dependence of the fraction of particles assembled in different forms. Down-triangles correspond to monomers, up-triangles to quartets, squares to octamers and circles to quadruplexes.
Global Fitting Approach, supplied by Genfit Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/global+fitting+approach/pmc04038801-160-1-1?v=Genfit+Inc
Average 90 stars, based on 1 article reviews
global fitting approach - by Bioz Stars, 2026-07
90/100 stars

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1) Product Images from "GENFIT : software for the analysis of small-angle X-ray and neutron scattering data of macro­molecules in solution"

Article Title: GENFIT : software for the analysis of small-angle X-ray and neutron scattering data of macro­molecules in solution

Journal: Journal of Applied Crystallography

doi: 10.1107/S1600576714005147

(Left) Experimental SAXS curves referring to d(pG) at 5 wt% concentration and different temperatures. From the bottom to the top: open squares 296.6 K, open circles 297.7 K, up-triangles 298.6 K, down-triangles 300.8 K, diamonds 302.7 K. The solid lines are the GENFIT global fit curves. The scattering curves are scaled by an appropriate factor for the sake of clarity. (Right) Temperature dependence of the fraction of particles assembled in different forms. Down-triangles correspond to monomers, up-triangles to quartets, squares to octamers and circles to quadruplexes.
Figure Legend Snippet: (Left) Experimental SAXS curves referring to d(pG) at 5 wt% concentration and different temperatures. From the bottom to the top: open squares 296.6 K, open circles 297.7 K, up-triangles 298.6 K, down-triangles 300.8 K, diamonds 302.7 K. The solid lines are the GENFIT global fit curves. The scattering curves are scaled by an appropriate factor for the sake of clarity. (Right) Temperature dependence of the fraction of particles assembled in different forms. Down-triangles correspond to monomers, up-triangles to quartets, squares to octamers and circles to quadruplexes.

Techniques Used: Concentration Assay



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(Left) Experimental SAXS curves referring to d(pG) at 5 wt% concentration and different temperatures. From the bottom to the top: open squares 296.6 K, open circles 297.7 K, up-triangles 298.6 K, down-triangles 300.8 K, diamonds 302.7 K. The solid lines are the <t>GENFIT</t> <t>global</t> fit curves. The scattering curves are scaled by an appropriate factor for the sake of clarity. (Right) Temperature dependence of the fraction of particles assembled in different forms. Down-triangles correspond to monomers, up-triangles to quartets, squares to octamers and circles to quadruplexes.
Global Fitting Approach, supplied by Genfit Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/global+fitting+approach/pmc04038801-160-1-1?v=Genfit+Inc
Average 90 stars, based on 1 article reviews
global fitting approach - by Bioz Stars, 2026-07
90/100 stars
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(Left) Experimental SAXS curves referring to d(pG) at 5 wt% concentration and different temperatures. From the bottom to the top: open squares 296.6 K, open circles 297.7 K, up-triangles 298.6 K, down-triangles 300.8 K, diamonds 302.7 K. The solid lines are the <t>GENFIT</t> <t>global</t> fit curves. The scattering curves are scaled by an appropriate factor for the sake of clarity. (Right) Temperature dependence of the fraction of particles assembled in different forms. Down-triangles correspond to monomers, up-triangles to quartets, squares to octamers and circles to quadruplexes.
Global Fitting Approach Graphpad Prism V.4.02, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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(Left) Experimental SAXS curves referring to d(pG) at 5 wt% concentration and different temperatures. From the bottom to the top: open squares 296.6 K, open circles 297.7 K, up-triangles 298.6 K, down-triangles 300.8 K, diamonds 302.7 K. The solid lines are the GENFIT global fit curves. The scattering curves are scaled by an appropriate factor for the sake of clarity. (Right) Temperature dependence of the fraction of particles assembled in different forms. Down-triangles correspond to monomers, up-triangles to quartets, squares to octamers and circles to quadruplexes.

Journal: Journal of Applied Crystallography

Article Title: GENFIT : software for the analysis of small-angle X-ray and neutron scattering data of macro­molecules in solution

doi: 10.1107/S1600576714005147

Figure Lengend Snippet: (Left) Experimental SAXS curves referring to d(pG) at 5 wt% concentration and different temperatures. From the bottom to the top: open squares 296.6 K, open circles 297.7 K, up-triangles 298.6 K, down-triangles 300.8 K, diamonds 302.7 K. The solid lines are the GENFIT global fit curves. The scattering curves are scaled by an appropriate factor for the sake of clarity. (Right) Temperature dependence of the fraction of particles assembled in different forms. Down-triangles correspond to monomers, up-triangles to quartets, squares to octamers and circles to quadruplexes.

Article Snippet: A GENFIT global fitting approach was used to derive the concentrations and sizes of the different scattering particles existing in solution, as a function of temperature.

Techniques: Concentration Assay